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Takinib (Standard)

(Synonyms: EDHS-206 (Standard))

Takinib (Standard) is the analytical standard of Takinib. This product is intended for research and analytical applications. Takinib (EDHS-206) is an orally active and selective TAK1 inhibitor (IC50=9.5 nM), more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib is an inhibitor of autophosphorylated TAK1 that non-competitively binds within the ATP binding pocket. Takinib induces apoptosis following TNFα stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. Takinib is also a P. falciparum protein kinase 9 (PfPK9) inhibitor (KD(app) of 0.46 μM).

For research use only. We do not sell to patients.

  • CAS No.: 1111556-37-6
  • Formula: C18H18N4O2
  • Molecular Weight:322.36
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Takinib (Standard) Chemical Structure
    Takinib (Standard) Chemical Structure
CAS No.: 1111556-37-6
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • Takinib (Standard) Chemical Structure
    Takinib (Standard) Chemical Structure
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  • Takinib (Standard)