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Securitinine

Securitinine is a Securinega alkaloid. Securitinine can be derived from the wood of Japanese medicinal plant Securinega suffruticosa var.

For research use only. We do not sell to patients.

CAS No.: 13861-71-7
Formula: C₁₄H₁₇NO₃
Molecular Weight:247.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Securitinine Chemical Structure

CAS No.: 13861-71-7

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Sample (0.1mg)

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(In Japan)

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Securitinine is a Securinega alkaloid. Securitinine can be derived from the wood of Japanese medicinal plant Securinega suffruticosa var^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>10 μM Compound: 11	Cytotoxicity against human A549 cells after 48 hrs by SRB assay Cytotoxicity against human A549 cells after 48 hrs by SRB assay	[PMID: 31082231]
BV-2	IC₅₀	31.5 μM Compound: 11	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production after 24 hrs by Griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production after 24 hrs by Griess assay	[PMID: 31082231]
HCT-15	IC₅₀	>10 μM Compound: 11	Cytotoxicity against human HCT15 cells after 48 hrs by SRB assay Cytotoxicity against human HCT15 cells after 48 hrs by SRB assay	[PMID: 31082231]
SK-MEL-2	IC₅₀	>10 μM Compound: 11	Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay	[PMID: 31082231]
SK-OV-3	IC₅₀	>10 μM Compound: 11	Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay	[PMID: 31082231]

Chemical Information

CAS No. 13861-71-7
Molecular Weight 247.29
Formula C₁₄H₁₇NO₃
SMILES

O=C(O1)C=C2[C@@]13[C@@](C[C@@H](OC)CC4)([H])N4[C@](C3)([H])C=C2
Structure Classification
- Alkaloids
- Pyridine Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ohsaki A, et al. Securinega alkaloids from the wood of Securinega suffruticosa var. amamiensis. J Nat Prod. 2007 Dec;70(12):2003-5. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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