Hapten

Photolumazine III (PLIII) is a microbial metabolite and derivative of Riboflavin (HY-B0456). Photolumazine III binds MR1 with high specificity. Photolumazine III supports efficient TCR binding. Photolumazine III acts as an antigen to activate cells. Responses to Photolumazine III trigger immune reactions.

N-Phthaloylglycine (Phthaloyl glycine) is a Type II fragmentary hapten (FX-type) with antimicrobial activity. N-Phthaloylglycine acts against Candida albicans, Escherichia coli, and Staphylococcus epidermidis. N-Phthaloylglycine can be used for the research of fungal and bacterial infection.

DOTA-biotin is a DOTA-based small molecule hapten. DOTA-biotin has low tissue and whole-body retention in mice 4 h postinjection.

6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells.

Methyl 2-Octynoate is a hapten.

RL-6-Me-7-OH is a hapten that activates human and mouse MAIT cells (EC₅₀ = 25 µM). RL-6-Me-7-OH can be combined with carrier proteins and used in antigen design. RL-6-Me-7-OH can be used in inflammation and immunity research.

Fluorescein-6-isothiocyanate is a fluorescent isomeric haptenic probes with K_ds of 8.74, 2.72 and 1.88 for N-Acetyl-L-Lysine, normal mouse IgG and 4-4-20, respectively.

4-(N-Phthalimidoyl)butanoic acid (compound FB) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 4-(N-Phthalimidoyl)butanoic acid can be combined with carrier proteins and used in antigen design.

6-N-Phthalimidoy hexanoic acid (compound FH) is a hapten with a carboxyl group at the end of its spacer arm, suitable for reacting with free amine groups of proteins. 6-N-Phthalimidoy hexanoic acid can be combined with carrier proteins and used in antigen design.

Glucosamine-biotin adduct is a hapten and can be conjugated to hsIgG.

Mannosamine–biotin adduct is a hapten. Mannosamine–biotin adduct conjugated to hsIgG significantly reduces antibody immune responses against hsIgG.

IMP 245 is a symmetric di-HSG bivalent hapten. IMP 245 has low toxicity, high affinity binding to available antibodies and absence of cross reactivity or non-specific binding with body components.

IMP 241 is a di-HSG bivalent hapten.

AG8.0 is a symmetric di-HSG bivalent hapten. AG8.0 is stable in vivo for 24 h.

SG62 is an amine nicotine haptenand can be used for the study of nicotine dependence.

TETS-C4-acid (Compound 2d) is a hapten coupled directly to a carrier protein through a carboxylic acid functionality. TETS-C4-acid (Compound 2d) can be used to detect tetramethylenedisulfotetramine (TETS).

TETS-Methyl benzoate(compound 2j) is a haptendirectly conjugated to the carrier protein via carboxylic acid function using the standard activated ester method.

Dicamba 1-azidopropane (DCn) is an immunizing and heterologous hapten. Dicamba 1-azidopropane can be used to generate monoclonal antibodies specific of Dicamba.

Cyanazine-3-mercaptopropanoic acid (compound 6), a coating hapten, is a stable carrier-hapten complex. Polyclonal antibody obtained were with a high titer, with the IC₅₀ of 10.2 ng/mL for Cyanazine-3-mercaptopropanoic acid.

Hal-HS, a happen, fully protects and highlights the main functional groups of the molecule, thereby completely exposing it to the immune system. Hal-HS can be covalently attached to BSA via the active ester method to obtain hapten–protein conjugates (Hal-BSA) as immunogen.