PSG5 - pregnancy specific beta-1-glycoprotein 5 Gene

Also Known as PSG; FL-NCA-3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5673

About PSG5

Cytogenetic location: 19q13.31 Genomic coordinates (GRCh38): 19:43,167,743-43,186,536 (from NCBI)

This gene has 11 transcripts (splice variants), 628 orthologues and 24 paralogues. Restricted expression toward placenta (RPKM 117.8).

Summary

The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

PSG5 Products (2)

mRNA Protein Name
NM_001130014.2 NP_001123486.1 pregnancy-specific beta-1-glycoprotein 5 precursor
NM_002781.4 NP_002772.3 pregnancy-specific beta-1-glycoprotein 5 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21982860 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PSG5 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (41 - 128)

Ig_2

Ig_2: Immunoglobulin domain (154 - 235)

Ig_2

Ig_2: Immunoglobulin domain (242 - 320)

  • 0
  • 100
  • 200
  • 300
  • 335 a.a.
Protein Preferred Names Protein Names

pregnancy-specific beta-1-glycoprotein 5

  • PS-beta-G-5

PSG5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PSG5 Q15238 TIE1 Homo sapiens P35590
Protein Array
21982860
Intra
PSG5 Q15238 TIE1 Homo sapiens P35590
SPR
21982860
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant PSG5 Proteins

Cat. No. Product Name Accession Purity
HY-P71238 PS-beta-G-5 Protein, Human (HEK293, His) AAH12607.1 (Q35-I335) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11284 PSG5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown