UNK - unk zinc finger Gene

Also Known as ZC3H5; UNKEMPT; ZC3HDC5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 85451

About UNK

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:75,784,806-75,825,799 (from NCBI)

This gene has 8 transcripts (splice variants), 204 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 4.4), spleen (RPKM 4.1) and 25 other tissues.

Summary

Enables mRNA CDS binding activity. Involved in cell morphogenesis involved in neuron differentiation and negative regulation of cytoplasmic translation. Part of polysome. [provided by Alliance of Genome Resources, Apr 2022]

UNK Products (1)

mRNA Protein Name
NM_001080419.3 NP_001073888.2 RING finger protein unkempt homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA CDS binding IDA
IDA: Inferred from direct assay
25737280 GOA
Biological Process GO Annotation Evidence References Source
involved in cell morphogenesis involved in neuron differentiation IMP
IMP: Inferred from mutant phenotype
25737280 GOA
involved in negative regulation of cytoplasmic translation IMP
IMP: Inferred from mutant phenotype
25737280 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
25737280 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UNK Protein Structure

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (294 - 319)

  • 0
  • 200
  • 400
  • 600
  • 810 a.a.
Protein Preferred Names Protein Names

RING finger protein unkempt homolog

  • unk family zinc finger

Related Diseases

Diseases Alias
Adhesions Of Uterus

  • Intrauterine Adhesions

  • Intrauterine Synechiae

  • Band Of Uterus

  • Asherman Syndrome

  • Internal Adhesion Of Uterus

  • Internal Band Of Uterus
Endometrial Disease

  • Endometrial Disorder

  • Endometrial Diseases
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P2322 Iturin A 98.53% Unkown
HY-100243A Norcisapride / Unkown
HY-RS15479 UNK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19570 Unk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26067 Unk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus UNK MGD MGI:2442456
Felis catus UNK VGNC VGNC:66837
Macaca mulatta UNK VGNC VGNC:79803
Canis familiaris UNK VGNC VGNC:48148
Bos taurus UNK VGNC VGNC:36678
Rattus norvegicus UNK RGD RGD:1309224
Others UNK NCBI