2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Jingzhaotoxin XI

Jingzhaotoxin XI (JZTX-XI) is a sodium conductance inhibitor with an IC50 of 124 nM. Jingzhaotoxin XI slows the fast inactivation (EC50=1.18±0.2 μM) of Nav1.5 expressed in Chinese hamster ovary (CHO-K1) cells.

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Jingzhaotoxin XI

Jingzhaotoxin XI Chemical Structure

CAS No. : 921955-96-6

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Jingzhaotoxin XI Related Antibodies

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Description

Jingzhaotoxin XI (JZTX-XI) is a sodium conductance inhibitor with an IC50 of 124 nM. Jingzhaotoxin XI slows the fast inactivation (EC50=1.18±0.2 μM) of Nav1.5 expressed in Chinese hamster ovary (CHO-K1) cells[1].

IC50 & Target

IC50: 124 nM (sodium conductance)[1]
Molecular Weight

3726.27

Formula

C158H234N44O47S7
CAS No.
Sequence

Glu-Cys-Arg-Lys-Met-Phe-Gly-Gly-Cys-Ser-Val-Asp-Ser-Asp-Cys-Cys-Ala-His-Leu-Gly-Cys-Lys-Pro-Thr-Leu-Lys-Tyr-Cys-Ala-Trp-Asp-Gly-Thr-Phe-NH2 (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys28)
Sequence Shortening

ECRKMFGGCSVDSDCCAHLGCKPTLKYCAWDGTF-NH2 (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys28)
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Jingzhaotoxin XI Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Jingzhaotoxin XI921955-96-6JZTX-XISodium ChannelNa channelsNa+ channelsChilobrachys jingzhaoCHO-K1Inhibitorinhibitorinhibit

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