Oleoside dimethylester
Oleoside dimethylester is a secoiridoid glucoside found in the fruits of Ligustrum lucidum. Oleoside dimethylester exhibits inhibitory activity against type 3 parainfluenza virus (Para 3) and respiratory syncytial virus (RSV), with IC50 values of 20.8 and 83.2 μg/mL. Oleoside dimethylester also shows antioxidant effect.
For research use only. We do not sell to patients.
- CAS No.: 30164-95-5
- Formula: C18H26O11
- Molecular Weight:418.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
>80 μM
Compound: 10
|
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess reagent-based assay
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess reagent-based assay
|
[PMID: 32936639] |
| SK-BR-3 | IC50 |
>15 μM
Compound: 18
|
Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT reduction assay
Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT reduction assay
|
[PMID: 28551177] |
Chemical Information
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CAS No. 30164-95-5
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Molecular Weight 418.39
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Formula C18H26O11
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SMILES
COC(C[C@H]1/C([C@@H](OC=C1C(OC)=O)O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)=C\C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)