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製品番号: HY-D3182

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AldRed 588-A

AldeRed 588-A is a fluorescent labeling reagent and a substrate for aldehyde dehydrogenase (ALDH). AldeRed 588-A is metabolized by functionally active ALDH enzymes, thereby specifically labeling viable ALDH^bright cell populations with red-shifted fluorescence. AldeRed 588-A supports one-step isolation and sorting of ALDH-expressing cells (including normal stem cells and cancer stem cells), and can be used in combination with green fluorophores for multicolor experimental applications. AldeRed 588-A is widely applicable to research related to various cancers such as bladder cancer, breast cancer, and head and neck cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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CAS 番号: 2252329-12-5
分子式: C₁₈H₁₇BF₂N₄O₂
分子量:370.16

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

AldRed 588-A 構造式

CAS 番号: 2252329-12-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Aldehyde Dehydrogenase (ALDH) アイソフォーム固有の製品をすべて表示 :

体外実験

AldRed 588-A identifies ALDH^bright cell populations in cell lines expressing functional ALDH with potency comparable to that of ALDEFLUOR^TM, and enables one-step isolation of ALDH-expressing cells when co-incubated with ALDEFLUOR^TM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2252329-12-5
分子量 370.16
分子式 C₁₈H₁₇BF₂N₄O₂
SMILES

O=CCNC(CCC1=[N]2[B+3]([F-])([F-])[N-]3C(C4=CC=CN4)=CC=C3C=C2C=C1)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Dollé L, et al. Next generation of ALDH substrates and their potential to study maturational lineage biology in stem and progenitor cells. Am J Physiol Gastrointest Liver Physiol. 2015;308(7):G573-G578. [Content Brief]

[2]. Asbrock N, et al. A red-shifted fluorescent substrate for aldehyde dehydrogenase, AldeRed 588-A, for labeling viable ALDH-positive cells[J]. Cancer Research, 2016, 76(14_Supplement): 2508-2508.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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希釈計算機

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濃度 _(開始) 濃度 _(開始)

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濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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AldRed 588-A

Aldehyde Dehydrogenase (ALDH) アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

AldRed 588-A 関連分類

HY-D3182 関連分類