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製品番号: HY-119925

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Amaralin

Amaralin is a sesquiterpene lactone with analgesic activity, which exists in the leaves and stems of Helenium amarum (Raf.) H. Rock. When administered subcutaneously, Amaralin produces analgesic effects in the mouse tail-flick test. When administered subcutaneously, Amaralin inhibits acetic acid-induced writhing syndrome in mice. Amaralin can be used for pain-related research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 6831-10-3
分子式: C₁₅H₂₀O₄
分子量:264.32

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Amaralin 構造式

CAS 番号: 6831-10-3

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生物活性

製品説明

体外実験

Amaralin (compound Ia) is a pseudoguaianolide sesquiterpene lactone. It readily forms monoacetate at room temperature^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Amaralin (compound Ia) (10-25 mg/kg; s.c.) produces potent analgesic effects in mouse tail flick test and inhibits acetic acid-induced writhing syndrome in mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 6831-10-3
分子量 264.32
分子式 C₁₅H₂₀O₄
SMILES

C[C@]12[C@@]([C@@]3([C@]([C@@H]1O)(O3)[H])[H])([C@H](C)C[C@]4([C@](C2)(C(=C)C(=O)O4)[H])[H])[H]
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
- Plants
- Compositae
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Lucas R A, et al. A New Sesquiterpene Lactone with Analgesic Activity from Helenium amarum (Raf.) H. Rock. The Journal of Organic Chemistry, 1964, 29(6): 1549-1554.

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