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製品番号: HY-162721

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Anticancer agent 242

Anticancer agent 242 (7) possesses anticancer activity in A2780 (IC₅₀ = 0.24 μM, ovarian adenocarcinoma), A2780cis (IC₅₀ = 0.45 μM, resistant derivative of A2780), CCD18Co (IC₅₀ = 0.59 μM, non-malignant human fibroblasts), A549 (IC₅₀ = 0.32 μM, lung carcinoma), HT29 (IC₅₀ = 0.26 μM, colorectal adenocarcinoma), and MCF7 (IC₅₀ = 0.55 μM, breast adenocarcinoma).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₅₉H₇₂ClF₃N₆O₅S₂
分子量:1101.82

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Anticancer agent 242 構造式

容量

価格（税別）

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数量

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	0.24 μM Compound: 7	Cytotoxicity against human A2780 cells incubated for 72 hrs by SRB assay Cytotoxicity against human A2780 cells incubated for 72 hrs by SRB assay	[PMID: 38996651]
A2780cis	IC₅₀	0.45 μM Compound: 7	Cytotoxicity against human A2780cis cells incubated for 72 hrs by SRB assay Cytotoxicity against human A2780cis cells incubated for 72 hrs by SRB assay	[PMID: 38996651]
A549	IC₅₀	0.59 μM Compound: 7	Cytotoxicity against human A549 cells incubated for 72 hrs by SRB assay Cytotoxicity against human A549 cells incubated for 72 hrs by SRB assay	[PMID: 38996651]
CCD-18Co	IC₅₀	0.55 μM Compound: 7	Cytotoxicity against human CCD-18Co cells incubated for 72 hrs by SRB assay Cytotoxicity against human CCD-18Co cells incubated for 72 hrs by SRB assay	[PMID: 38996651]
HT-29	IC₅₀	0.32 μM Compound: 7	Cytotoxicity against human HT-29 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HT-29 cells incubated for 72 hrs by SRB assay	[PMID: 38996651]
MCF7	IC₅₀	0.26 μM Compound: 7	Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay	[PMID: 38996651]

化学情報

分子量 1101.82
分子式 C₅₉H₇₂ClF₃N₆O₅S₂
SMILES

FC1=C(F)C(SCCC2=CC=C(C(N3CCN(C(C4=CC=CC=C4C5=C(C=C/6)C(OC7=C5C=CC(N(CC)CC)=C7)=CC6=[N+](CC)\CC)=O)CC3)=O)C=C2)=C(F)C(NC8CCCCCCCCCCC8)=C1S(=O)(N)=O.[Cl-]
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (269 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Niels V Heise, et al. Dehydroabietylamine-substituted trifluorobenzene sulfonamide rhodamine B hybrids as anticancer agents overcoming drug resistance. Eur J Med Chem. 2024 Jul 10:276:116667. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

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濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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