BIM5078
BIM5078 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BIM5078 represses insulin promoter activity through HNF4α antagonism. BIM5078 can be used for the research of cancer and diabetes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 337506-43-1
- 分子式: C14H10ClN3O4S
- 分子量:351.76
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Nuclear Hormone Receptor 4A/NR4A アイソフォーム固有の製品をすべて表示
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生物活性
hepatocyte nuclear factor 4α (HNF4α)[1]
BIM5078 (0.63-5μM; 48 h) inhibits the expression of endogenous insulin in T6PNE cells with IC50 value of 930 nM[1].
BIM5078 (2.5-10 μM; 5-48 h) inhibits HNF4α gene expression in HepG2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 337506-43-1
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分子量 351.76
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分子式 C14H10ClN3O4S
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SMILES
[O-][N+](C1=CC=C(C(S(=O)(N2C3=C(N=C2C)C=CC=C3)=O)=C1)Cl)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
BIM5078 関連分類
HY-119971 関連分類
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