Captopril EP Impurity E
Captopril EP Impurity E is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 23500-15-4
- 分子式: C9H15NO3
- 分子量:185.22
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | EC50 |
>250 μM
Compound: L-C1
|
Cytotoxicity against human HeLa cells incubated for 72 hrs by alamar blue cell viability assay
Cytotoxicity against human HeLa cells incubated for 72 hrs by alamar blue cell viability assay
|
[PMID: 39013490] |
化学情報
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CAS 番号 23500-15-4
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分子量 185.22
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分子式 C9H15NO3
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SMILES
O=C(O)[C@H]1N(C(C(C)C)=O)CCC1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[2]. Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64(11):2263-2268. [Content Brief]
[3]. Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)