CB2R agonist 1
CB2R agonist 1 is a selective ligand of cannabinoid receptor subtype 2 (CB2R) with an EC50 value of 0.56 µM. CB2R agonist 1 has high affinity and excellent selectivity for human CB2R and CB1R respectively. CB2R agonist 1 regulates the production of pro-inflammatory cytokines and anti-inflammatory cytokines and play an immunomodulatory role.
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- CAS 番号: 1817633-49-0
- 分子式: C22H32N2O
- 分子量:340.50
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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CB2R 0.56 μM (EC50) |
CB2R agonist 1 (Compound 4) (1 μM and 10 μM; 24 h) increases the production of IL-4 and IL-10 anti-inflammatory cytokines and reduces the production of TNF-α, IFN-γ, IL-1β and IL-6 pro-inflammatory cytokines in monocytes and macrophages with concentration-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1817633-49-0
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分子量 340.50
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分子式 C22H32N2O
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SMILES
O=C(C1=C(NCCCCC)C=CC=C1)NC23CC4CC(C3)CC(C2)C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)