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United States

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製品番号: HY-187119

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CC13401

CC13401 is an aldose reductase (ALR2) inhibitor with an IC₅₀ of 41.41 μM in rats. CC13401 inhibits the NADPH-dependent reduction reaction catalyzed by ALR2. CC13401 can be used in studies on the mechanisms related to the polyol pathway and diabetic complications.

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CAS 番号: 158575-73-6
分子式: C₁₇H₁₅NO₄
分子量:297.31

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

CC13401 構造式

CAS 番号: 158575-73-6

価格（税別）

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target

^[1]

ALR2

41.41 μM (IC₅₀)

体外実験

Carbohydrate Metabolism

CC13401 (compound 9) tested as a racemate, specifically inhibits rat lens-derived aldose reductase with an IC₅₀ of 41.41 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 158575-73-6
分子量 297.31
分子式 C₁₇H₁₅NO₄
SMILES

O=C(N1C2=CC=CC=C2C[C@@H]1C(O)=O)OCC3=CC=CC=C3
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Cosconati S, et al. Pursuing aldose reductase inhibitors through in situ cross-docking and similarity-based virtual screening. Journal of medicinal chemistry. 2009 Sep 24;52(18):5578-81. [Content Brief]

Calculators

モル濃度計算機

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希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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