CCT369834
CCT369834 is an ATP-competitive HSET inhibitor with an IC50 of 39 nM. CCT369834 is a trans-cyclooctene-tagged probe. CCT369834 and HSET specifically co-localize on mitotic spindles. CCT369834 can be used for the research of cancer.
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- CAS 番号: 2902671-78-5
- 分子式: C38H49N7O7S
- 分子量:747.90
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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生物活性
製品説明
IC50 & Target
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HSET 39 nM (IC50) |
体外実験
CCT369834 inhibits recombinant full-length HSET (IC50 = 39 nM)[1].
CCT369834 (3 μM; 45 min) shows clear Cy5-labeled mitotic spindle signals in proTAME-treated DLD1 4N cells, which overlap with endogenous HSET signals[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2902671-78-5
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分子量 747.90
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分子式 C38H49N7O7S
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SMILES
O=C(N[C@H](CC(NC1=NC(C)=C(S1)C(OCCC)=O)=O)CCCN(CC#CCNC(O[C@H]2CCC/C=C/CC2)=O)C)C3=CC=CC(C4=NOC(C)=N4)=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CCT369834 関連分類
HY-180304 関連分類
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