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United States

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製品番号: HY-162637

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CTL26

CTL26 is a potent and orally active α-glucosidase inhibitor with an IC₅₀ value of 2.81 µM. CTL26 shows anti-diabetic efficacy.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 3047448-30-3
分子式: C₂₅H₁₈N₆O₃S
分子量:482.51

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

CTL26 構造式

CAS 番号: 3047448-30-3

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

CTL26 is a potent and orally active α-glucosidase inhibitor with an IC₅₀ value of 2.81 µM. CTL26 shows anti-diabetic efficacy^[1].

IC₅₀ & Target

IC₅₀: 2.81 µM (α-glucosidase)^[1]

体内実験

CTL26 (25, 50 mg/kg; p.o.; daily for 4 weeks) shows anti-diabetic efficacy in streptozocin (HY-13753)-induced diabetes mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

10-15g, SPF C57/6 J male mice (STZ-induced diabetes)^[1]
Dosage:

25, 50 mg/kg
Administration:

P.o.; daily for 4 weeks
Result:

Exhibited continuously decreasing fasting blood glucose (FBG) levels, decreased the serum total cholesterol (TC) and triglycerides (TG) levels.

化学情報

CAS 番号 3047448-30-3
分子量 482.51
分子式 C₂₅H₁₈N₆O₃S
SMILES

O=C(NNC(NC1=CC([N+]([O-])=O)=CC=C1)=S)C2=CC3=C(C(C4=CC=CC=C4)=N2)NC5=CC=CC=C53
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (271 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Liang B, et al. Novel thiosemicarbazide-based β-carboline derivatives as α-glucosidase inhibitors: Synthesis and biological evaluation. Eur J Med Chem. 2024 Jun 12;275:116595. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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