DOPE-PEG10000-NHS
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子量:10000 (Average)
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
生物活性
-
化学情報
- 純度とドキュメンテーション
-
Help & FAQs
生物活性
The structure of DOPE-PEG-NHS comprises three key components that work synergistically:
DOPE: Containing two oleoyl groups (C18:1), it imparts excellent membrane fluidity and promotes membrane fusion under acidic conditions (such as endosome escape).
PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
NHS: Acts as a reaction interface, reacting efficiently with molecules containing primary amino groups (such as antibodies and peptides) under mild conditions to form stable covalent bonds.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
分子量 10000 (Average)
-
SMILES
CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COP(OCCNC(COCCOCC(ON(C(CC1)=O)C1=O)=O)=O)(O)=O)=O.[n]
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Powered by Bioz