ERG-IN-8
Based on 2 publication(s) in Google Scholar
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 926068-88-4
- 分子式: C23H26N2O2S
- 分子量:394.53
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
MedChemExpress(MCE)の使用を引用している文献 ERG-IN-8
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生物活性
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
0.16 μM
Compound: 14, AMTB
|
Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 mins before menthol challenge measured after 5 mins
Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 mins before menthol challenge measured after 5 mins
|
[PMID: 20965726] |
| HEK293 | IC50 |
0.19 μM
Compound: 14, AMTB
|
Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mins before icilin challenge measured after 5 mins
Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mins before icilin challenge measured after 5 mins
|
[PMID: 20965726] |
| HEK293 | IC50 |
7.3 μM
Compound: AMTB
|
Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux preincubated for 60 mins followed by menthol addition by Fluo-4 NW dye based fluorimetric method
Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of menthol-induced calcium flux preincubated for 60 mins followed by menthol addition by Fluo-4 NW dye based fluorimetric method
|
[PMID: 32787109] |
化学情報
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CAS 番号 926068-88-4
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分子量 394.53
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分子式 C23H26N2O2S
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SMILES
O=C(C=1C=CC=CC1OCC=2C=CC=C(C2)C)N(CC=3SC=CC3)CCCN
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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J Ethnopharmacol
2024 Mar 25:322:117581. PMID: 38103845 -
BMC Cancer
Enhanced anti-cancer effect of AMTB hydrochloride via chitosan nanoparticles in pancreatic cancer. [Abstract]2025 May 26;25(1):944. PMID: 40420025
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)