ARID3A - AT-rich interaction domain 3A Gene

Also Known as DRIL1; DRIL3; BRIGHT; E2FBP1

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 1820

About ARID3A

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:925,732-975,939 (from NCBI)

This gene has 7 transcripts (splice variants), 191 orthologues and 2 paralogues. Broad expression in placenta (RPKM 13.1), bone marrow (RPKM 2.3) and 16 other tissues.

Summary

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]

ARID3A Products (1)

mRNA	Protein	Name
NM_005224.3	NP_005215.1	AT-rich interactive domain-containing protein 3A

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	参考文献	由来
enables protein binding	IPI IPI: Inferred from physical interaction	19214191	GOA

Cellular Component GO Annotation	Evidence	参考文献	由来
located in membrane raft	IDA IDA: Inferred from direct assay	21955986	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARID3A Protein Structure

ARID

0
100
200
300
400
500
593 a.a.

Protein Preferred Names	Protein Names
AT-rich interactive domain-containing protein 3A	ARID domain-containing 3A

ARID3A Protein-protein interaction Information

Type	タンパク質名	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	参考文献
Intra	ARID3A	Q99856	MORF4L1	Homo sapiens	Q9UBU8-2	Validated Y2H	32296183
Intra	ARID3A	Q99856	REP15	Homo sapiens	Q6BDI9	Y2H Array	32296183
Intra	ARID3A	Q99856	REP15	Homo sapiens	Q6BDI9	Y2H Prey Pooling	32296183
Intra	ARID3A	Q99856	ANKRD11	Homo sapiens	X5D778	Validated Y2H	32296183
Intra	ARID3A	Q99856	BTK	Homo sapiens	Q06187	Anti Bait CoIP	19214191
Intra	ARID3A	Q99856	BTK	Homo sapiens	Q06187	Density Sedimentation	19214191
Intra	ARID3A	Q99856	NOTCH2NLA	Homo sapiens	Q7Z3S9	Y2H Array	25416956
Intra	ARID3A	Q99856	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	ARID3A	Q99856	KRT31	Homo sapiens	Q15323	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS00969	ARID3A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21092	Arid3a Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27610	Arid3a Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Macaca mulatta	ARID3A	VGNC	VGNC:69930
Bos taurus	ARID3A	VGNC	VGNC:26126
Canis familiaris	ARID3A	VGNC	VGNC:38095
Mus musculus	ARID3A	MGD	MGI:1328360
Rattus norvegicus	ARID3A	RGD	RGD:1305299
Felis catus	ARID3A	VGNC	VGNC:59914
Others	ARID3A	NCBI