Ythdf2 - YTH N6-methyladenosine RNA binding protein 2 Gene

Also Known as HGRG8; NY-REN-2; 9430020E02Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 213541

Summary

Enables N6-methyladenosine-containing RNA binding activity. Involved in several processes, including gamete generation; hematopoietic stem cell proliferation; and negative regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in brain. Orthologous to human YTHDF2 (YTH N6-methyladenosine RNA binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ythdf2 Products (1)

mRNA Protein Name
NM_145393.4 NP_663368.3 YTH domain-containing family protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables N6-methyladenosine-containing RNA reader activity IMP
IMP: Inferred from mutant phenotype
29855337 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in gamete generation IMP
IMP: Inferred from mutant phenotype
32943573 MGI
involved in hematopoietic stem cell proliferation IMP
IMP: Inferred from mutant phenotype
30065315 MGI
involved in mRNA catabolic process IMP
IMP: Inferred from mutant phenotype
29855337 MGI
involved in mRNA destabilization IMP
IMP: Inferred from mutant phenotype
29855337 MGI
involved in oocyte maturation IMP
IMP: Inferred from mutant phenotype
28867294 MGI
NOT involved in positive regulation of translational initiation IMP
IMP: Inferred from mutant phenotype
32943573 MGI
involved in regulation of cell adhesion IMP
IMP: Inferred from mutant phenotype
31959747 MGI
involved in regulation of hematopoietic stem cell differentiation IMP
IMP: Inferred from mutant phenotype
30065315 MGI
involved in regulation of mRNA stability IMP
IMP: Inferred from mutant phenotype
32943573 MGI
involved in regulation of meiotic cell cycle process involved in oocyte maturation IMP
IMP: Inferred from mutant phenotype
28867294 MGI
involved in regulation of neurogenesis IMP
IMP: Inferred from mutant phenotype
29855337 MGI
involved in spermatogonial cell division IMP
IMP: Inferred from mutant phenotype
31959747 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in cytoplasm IDA
IDA: Inferred from direct assay
28867294 MGI
located in nucleus IMP
IMP: Inferred from mutant phenotype
32943573 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

YTH domain-containing family protein 2

  • YTH domain family 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-154919 DC-Y13-27 Inhibitor 99.52% Unkown
HY-137341 SK-3-91 Degrader 98.33% Unkown
HY-173008 YTHDF2-IN-1 Inhibitor 99.42% Unkown
HY-169396 TAE648 Inhibitor 99.50% Unkown
HY-176848 SKLB-Y13 Inhibitor 98.44% Unkown
HY-174982 YTHDF2 ligand-1 Ligand 98.83% Unkown
HY-168610 YTH-IN-1 Inhibitor 98.66% Unkown
HY-RS15938 YTHDF2 Human Pre-designed siRNA Set A Inhibitor / Unkown
HY-175885 PROTAC FTO degrader 1 Inhibitor / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Ythdf2 NCBI NCBI:51441