ELP5 - elongator acetyltransferase complex subunit 5 Gene
Also Known as DERP6; MST071; HSPC002; MSTP071; C17orf81
生物種: Homo sapiens
About ELP5
This gene has 14 transcripts (splice variants), 1 gene allele and 177 orthologues. Broad expression in testis (RPKM 39.1), brain (RPKM 8.9) and 24 other tissues.
Summary
Predicted to contribute to tRNA binding activity. Predicted to be involved in positive regulation of cell migration and tRNA modification. Located in cytosol and nucleoplasm. Part of elongator holoenzyme complex. [provided by Alliance of Genome Resources, Apr 2022]
ELP5 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_015362.5 | NP_056177.4 | elongator complex protein 5 isoform 1 |
| NM_203413.3 | NP_981958.2 | elongator complex protein 5 isoform 2 |
| NM_203414.3 | NP_981959.2 | elongator complex protein 5 isoform 1 |
| NM_203415.4 | NP_981960.2 | elongator complex protein 5 isoform 1 |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
16713569 | GOA |
| Cellular Component GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
22854966 | GOA |
| part of elongator holoenzyme complex |
IDA
IDA: Inferred from direct assay
|
22854966 | GOA |
| part of elongator holoenzyme complex |
IPI
IPI: Inferred from physical interaction
|
22854966 | GOA |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
22854966 | GOA |
ELP5 Protein Structure
Elong_Iki1: Elongator subunit Iki1 (17 - 298)
- 0
- 100
- 200
- 300
- 316 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
elongator complex protein 5 |
|
ELP5 Protein-protein interaction Information
|
Type
|
タンパク質名 | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | 参考文献 |
|---|---|---|---|---|---|---|---|
|
Intra
|
ELP5 | Q8TE02 | ELP6 | Homo sapiens | Q0PNE2 | 22854966 | |
|
Intra
|
ELP5 | Q8TE02 | ELP4 | Homo sapiens | Q96EB1 | 22854966 |
関連疾患
| Diseases | Alias | |
|---|---|---|
| Tomato Allergy |
|
|
| Neuropathy, Hereditary Sensory And Autonomic, Type Iii |
|
|
| Benign Epilepsy With Centrotemporal Spikes |
|
|
Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Macaca mulatta | ELP5 | VGNC | VGNC:72146 |
| Bos taurus | ELP5 | VGNC | VGNC:28458 |
| Mus musculus | ELP5 | MGD | MGI:1859017 |
| Canis familiaris | ELP5 | VGNC | VGNC:40329 |
| Felis catus | ELP5 | VGNC | VGNC:61829 |
| Rattus norvegicus | ELP5 | RGD | RGD:1303303 |
| Others | ELP5 | NCBI |