FGF22 - fibroblast growth factor 22 Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 27006

About FGF22

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:639,879-644,373 (from NCBI)

This gene has 3 transcripts (splice variants), 182 orthologues and 21 paralogues. Biased expression in skin (RPKM 1.5), brain (RPKM 0.4) and 7 other tissues.

Summary

The protein encoded by this gene is a member of the Fibroblast Growth Factor (FGF) family. FGF Family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

FGF22 Products (2)

mRNA Protein Name
NM_001300812.3 NP_001287741.1 fibroblast growth factor 22 isoform 2 precursor
NM_020637.2 NP_065688.1 fibroblast growth factor 22 isoform 1 precursor

FGF22 Protein Structure

FGF

FGF: Fibroblast growth factor (41 - 165)

  • 0
  • 100
  • 170 a.a.
Protein Preferred Names Protein Names

fibroblast growth factor 22

  • FGF-22

Recombinant FGF22 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P700063AF Animal-Free FGF-22 Protein, Human (His-SUMO) Q9HCT0 (T23-S170) ≥ 95%, as determined by reducing SDS-PAGE.

関連疾患

Diseases Alias
Breast Giant Fibroadenoma

  • Giant Fibroadenoma

  • Giant Fibroadenoma Of Breast
Lacrimoauriculodentodigital Syndrome

  • Ladd Syndrome

  • Levy-Hollister Syndrome

  • Lacrimo-Auriculo-Dento-Digital Syndrome

  • LADD

  • Lacrimoauriculodento-Digital Syndrome

  • Levy Hollister Syndrome

  • Lard Syndrome

  • Lacrimoauriculoradiodental Syndrome

  • LADDS

  • Congenital Duodenal Obstruction Due To Malrotation Of Intestine
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-148432 FGF22-IN-1 Inhibitor 98.07% Unkown
HY-RS04899 FGF22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174699 Human FGF22 mRNA / Unkown
HY-RS19434 Fgf22 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25925 Fgf22 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Mus musculus FGF22 MGD MGI:1914362
Canis familiaris FGF22 VGNC VGNC:40849
Macaca mulatta FGF22 VGNC VGNC:72648
Bos taurus FGF22 VGNC VGNC:52233
Felis catus FGF22 VGNC VGNC:102584
Rattus norvegicus FGF22 RGD RGD:620177
Others FGF22 NCBI