Mast1 - microtubule associated serine/threonine kinase 1 Gene

Also Known as SAST; SAST170; 9430008B02Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 56527

Summary

Enables microtubule binding activity. Involved in brain development and Cytoskeleton organization. Located in membrane; neuron projection; and neuronal cell body. Is expressed in nervous system; neural retina; and skeletal muscle. Used to study mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations. Human ortholog(s) of this gene implicated in mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations. Orthologous to human MAST1 (microtubule associated serine/threonine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mast1 Products (1)

mRNA Protein Name
NM_019945.2 NP_064329.2 microtubule-associated serine/threonine-protein kinase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables microtubule binding IDA
IDA: Inferred from direct assay
30449657 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10404183 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in brain development IMP
IMP: Inferred from mutant phenotype
30449657 MGI
involved in cytoskeleton organization IDA
IDA: Inferred from direct assay
12477932 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in membrane IDA
IDA: Inferred from direct assay
10404183 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
30449657 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
30449657 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microtubule-associated serine/threonine-protein kinase 1

  • syntrophin associated serine/threonine kinase

  • syntrophin-associated serine-threonine protein kinase

Mast1 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Cross
Mast1 Q9R1L5 PTEN Homo sapiens P60484
Beta Galactosidase
15951562
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS02744 CLASP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08161 MAST1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22625 Mast1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29140 Mast1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Mast1 NCBI NCBI:22983