RAB11FIP3 - RAB11 family interacting protein 3 Gene

Also Known as CART1; FIP3-Rab11; Rab11-FIP3

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 9727

About RAB11FIP3

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:425,649-523,011 (from NCBI)

This gene has 11 transcripts (splice variants), 1 gene allele, 204 orthologues and 1 paralogue. Broad expression in kidney (RPKM 33.4), brain (RPKM 8.0) and 25 other tissues.

Summary

Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]

RAB11FIP3 Products (3)

mRNA Protein Name
NM_001142272.2 NP_001135744.2 rab11 family-interacting protein 3 isoform 2
NM_001370401.1 NP_001357330.1 rab11 family-interacting protein 3 isoform 3
NM_014700.4 NP_055515.1 rab11 family-interacting protein 3 isoform 1

RAB11FIP3 Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (206 - 262)

RBD-FIP

RBD-FIP: FIP domain (716 - 756)

  • 0
  • 200
  • 400
  • 600
  • 756 a.a.
Protein Preferred Names Protein Names

rab11 family-interacting protein 3

  • EF hands-containing Rab-interacting protein

RAB11FIP3 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
RAB11FIP3 O75154 RACGAP1 Homo sapiens Q9H0H5
IF
18511905
Intra
RAB11FIP3 O75154 RACGAP1 Homo sapiens Q9H0H5
Anti Bait CoIP
18511905
Intra
RAB11FIP3 O75154 RACGAP1 Homo sapiens Q9H0H5
Anti Tag CoIP
18511905
Intra
RAB11FIP3 O75154 RACGAP1 Homo sapiens Q9H0H5
Pull Down
18511905
Intra
RAB11FIP3 O75154 RACGAP1 Homo sapiens Q9H0H5
Competition Binding
18511905
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Congenital Muscular Dystrophy-Dystroglycanopathy A7

  • Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies Type A7

  • Mddga7

  • Walker-Warburg Syndrome Or Muscle-Eye-Brain Disease Ispd-Related

  • Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies, Type A7
Large Cell Medulloblastoma
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS11518 RAB11FIP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus RAB11FIP3 RGD RGD:1308952
Bos taurus RAB11FIP3 VGNC VGNC:33618
Macaca mulatta RAB11FIP3 VGNC VGNC:76500
Mus musculus RAB11FIP3 MGD MGI:2444431
Felis catus RAB11FIP3 VGNC VGNC:64469
Others RAB11FIP3 NCBI