Gentisuric acid
Based on 1 Customer Validation
Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.65%
- CAS 番号: 25351-24-0
- 分子式: C9H9NO5
- 分子量:211.17
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
製品説明
化学情報
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CAS 番号 25351-24-0
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性状 Solid
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分子量 211.17
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分子式 C9H9NO5
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Color White to off-white
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SMILES
OC1=CC(C(NCC(O)=O)=O)=C(O)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 83.33 mg/mL (394.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (614 KB)
- English - EN (614 KB)
- Français - FR (614 KB)
- Deutsch - DE (614 KB)
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- Español - ES (614 KB)
- Swedish - SV (614 KB)
- Italian - IT (614 KB)
- Korean - KR (614 KB)
- Portuguese - PT (614 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. DeBlassio JL, et al. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. Arch Biochem Biophys. 2000 Nov 1;383(1):46-55. [Content Brief]
[2]. Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomed Pharmacother. 2007 Feb-Apr;61(2-3):113-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7355 mL | 23.6776 mL | 47.3552 mL | 118.3880 mL |
| 5 mM | 0.9471 mL | 4.7355 mL | 9.4710 mL | 23.6776 mL | |
| 10 mM | 0.4736 mL | 2.3678 mL | 4.7355 mL | 11.8388 mL | |
| 15 mM | 0.3157 mL | 1.5785 mL | 3.1570 mL | 7.8925 mL | |
| 20 mM | 0.2368 mL | 1.1839 mL | 2.3678 mL | 5.9194 mL | |
| 25 mM | 0.1894 mL | 0.9471 mL | 1.8942 mL | 4.7355 mL | |
| 30 mM | 0.1579 mL | 0.7893 mL | 1.5785 mL | 3.9463 mL | |
| 40 mM | 0.1184 mL | 0.5919 mL | 1.1839 mL | 2.9597 mL | |
| 50 mM | 0.0947 mL | 0.4736 mL | 0.9471 mL | 2.3678 mL | |
| 60 mM | 0.0789 mL | 0.3946 mL | 0.7893 mL | 1.9731 mL | |
| 80 mM | 0.0592 mL | 0.2960 mL | 0.5919 mL | 1.4799 mL | |
| 100 mM | 0.0474 mL | 0.2368 mL | 0.4736 mL | 1.1839 mL |