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製品番号: HY-184076

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Ibrilparant

Ibrilparant is a LPA1 receptor antagonist with an IC₅₀ of 0.00753 μM. Ibrilparant exhibits LPA1 calcium flux antagonistic activity, with an IC₅₀ of 3.02 nM. Ibrilparant can be used in research related to various diseases such as cancer and inflammatory diseases.

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CAS 番号: 2978107-47-8
分子式: C₂₅H₃₁NO₅
分子量:425.52

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ibrilparant 構造式

CAS 番号: 2978107-47-8

容量

価格（税別）

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数量

Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target^[1]

LPA₁ Receptor

体外実験

Ibrilparant (compound 355) exerts potent functional antagonistic activity against LPA1 in CHO-K1 cells overexpressing human LPA1 and G15a, with an IC₅₀ of 0.00753 μM^[1].
Ibrilparant exhibits potent LPA1 calcium flux antagonistic activity in CHO-K1 cells overexpressing human LPA1 and G15a, with an IC₅₀ of 3.02 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2978107-47-8
分子量 425.52
分子式 C₂₅H₃₁NO₅
SMILES

O=C(C1(CCOCC1)NC2=CC=C(C(COC3CC3)=C2)C4=C(C)C(OCC)=CC=C4)O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Huang W, et al. Compounds and compositions for treating conditions associated with lpa receptor activity. WO2023160672A1. WIPO; 2023 Aug 31.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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