Indecainide
Indecainide (Ricainide) is an orally active antiarrhythmic agent. Indecainide can be used in the research of ventricular dysfunction. Indecainide has Na+-channel-blocking activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 74517-78-5
- 分子式: C20H24N2O
- 分子量:308.42
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Indecainide (4 mg/kg, p.o.) results in rapid absorption by 15 min[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Dogs[1]
-
Dosage:1-5 mg/kg
-
Administration:Intravenous injection
-
Result:Decreased cardiac contractility.
化学情報
-
CAS 番号 74517-78-5
-
分子量 308.42
-
分子式 C20H24N2O
-
SMILES
O=C(N)C1(C2=C(C=CC=C2)C3=C1C=CC=C3)CCCNC(C)C
-
別名
Ricainide; LY 135837 free base
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14(3):454-61. [Content Brief]
[2]. Lindstrom T D, et al. Metabolism of the antiarrhythmic agent, indecainide, in rats, dogs, and monkeys. Drug metabolism and disposition, 1984, 12(6): 691-697. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)