JMV 3002
Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 μg/kg.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 925239-03-8
- 分子式: C35H34N6O3
- 分子量:586.68
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
化学情報
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CAS 番号 925239-03-8
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分子量 586.68
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分子式 C35H34N6O3
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SMILES
O=C(C1=NC=CC=C1)N[C@@H](C2=NN=C(CCC3=CC=CC=C3)N2CC4=CC=C(OC)C=C4OC)CC5=CNC6=C5C=CC=C6
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)