KDM2B-IN-2
Based on 1 Customer Validation
KDM2B-IN-1 (Example 20) is an effective inhibitor of histone demethylase (KDM2B), with an IC50 value of 0.021 μM. KDM2B-IN-1 can be used in proliferative diseases, such as cancer research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.36%
- CAS 番号: 1965248-01-4
- 分子式: C21H26N4O2S2
- 分子量:430.59
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
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KDM2B 0.021 μM (IC50) |
体外実験
KDM2b (histone demethylase) belongs to the JmjC domain family and is responsible for removing methyl marks from histones (such as H3K36me2). Its abnormality is closely related to cancer and other diseases of excessive proliferation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1965248-01-4
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性状 Solid
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分子量 430.59
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分子式 C21H26N4O2S2
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Color Light brown to brown
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SMILES
O=S(C1=CC=C(C2=CSC=C2)C=C1)(N3C(N4CCN(C5CCC5)CC4)=NCC3)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 31.25 mg/mL (72.57 mM; ultrasonic and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.3224 mL | 11.6120 mL | 23.2239 mL | 58.0599 mL |
| 5 mM | 0.4645 mL | 2.3224 mL | 4.6448 mL | 11.6120 mL | |
| 10 mM | 0.2322 mL | 1.1612 mL | 2.3224 mL | 5.8060 mL | |
| 15 mM | 0.1548 mL | 0.7741 mL | 1.5483 mL | 3.8707 mL | |
| 20 mM | 0.1161 mL | 0.5806 mL | 1.1612 mL | 2.9030 mL | |
| 25 mM | 0.0929 mL | 0.4645 mL | 0.9290 mL | 2.3224 mL | |
| 30 mM | 0.0774 mL | 0.3871 mL | 0.7741 mL | 1.9353 mL | |
| 40 mM | 0.0581 mL | 0.2903 mL | 0.5806 mL | 1.4515 mL | |
| 50 mM | 0.0464 mL | 0.2322 mL | 0.4645 mL | 1.1612 mL | |
| 60 mM | 0.0387 mL | 0.1935 mL | 0.3871 mL | 0.9677 mL |
KDM2B-IN-2 関連分類
HY-139561 関連分類
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