KPC-2-IN-2
KPC-2-IN-2 (Compound 6c) is a potent Klebsiella pneumoniae carbapenemase (KPC-2) inhibitor (Ki=0.038 μM). KPC-2-IN-2 can enhance the activity of cefotaxime in KPC-2 expressing Escherichia coli.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3034185-71-9
- 分子式: C12H10BN3O2S
- 分子量:271.10
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
IC50: 0.038 μM (KPC-2)[1]
KPC-2-IN-2 (5 and 50 μg/mL; 24 h) treatment shows excellent tolerance in HEK-293[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HEK-293
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Concentration:5 and 50 μg/ml
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Incubation Time:24 hours
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Result:Tolerated well in the presence or absence of 30 μg/ml cefotaxime (>80% viability after 24 h).
化学情報
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CAS 番号 3034185-71-9
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分子量 271.10
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分子式 C12H10BN3O2S
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SMILES
OB(C1=CC=CC(N2C=C(N=N2)C3=CSC=C3)=C1)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)