L-689560
Based on 1 Customer Validation
L-689560 is a potent N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. L-689560 is widely used as a radiolabeled ligand in binding studies and used for study the roles of NMDA receptors in normal neurological processes as well as in diseases.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.29%
- CAS 番号: 139051-78-8
- 分子式: C17H15Cl2N3O3
- 分子量:380.23
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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NMDA Receptor |
L-689560 is a 2-carboxytetrahydroquinoline antagonist[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Adult male Sprague-Dawley (SD) rats middle cerebral artery occlusion (MCAO) model[1]
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Dosage:1 mg/kg
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Administration:IP
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Result:Significantly reduced the neuroprotective effect of glycine after glycine receptors.
化学情報
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CAS 番号 139051-78-8
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性状 Solid
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分子量 380.23
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分子式 C17H15Cl2N3O3
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Color White to off-white
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SMILES
O=C([C@@H]1NC2=C(C(Cl)=CC(Cl)=C2)[C@@H](NC(NC3=CC=CC=C3)=O)C1)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)