MB327
MB327 is a bipyridine nonoxime compound that restores neuromuscular function. MB327 restores the activity of nicotinamide acetylcholine receptors (nAChRs) for carbachol desensitization in a typical type II PAM manner. MB327 can neutralize nerve agent poisoning.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 61368-98-7
- 分子式: C21H32I2N2
- 分子量:566.30
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
化学情報
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CAS 番号 61368-98-7
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分子量 566.30
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分子式 C21H32I2N2
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SMILES
CC(C)(C)C1=CC=[N+](CCC[N+]2=CC=C(C(C)(C)C)C=C2)C=C1.[I-].[I-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Niessen K V, et al. In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2-and 3-regioisomers[J]. Toxicology Letters, 2018, 293: 190-197. [Content Brief]
[2]. Seeger T, et al. Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro[J]. Toxicology, 2012, 294(2-3): 80-84. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)