MDTF
Based on 1 Customer Validation
MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 95.64%
- 分子式: C16H10F4NNaO9S
- 分子量:491.30
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
MDTF (50 μM) increases hydrophilic character by substitution of a cyclohexyl ring and a MD-based FRET probe incubates in human plasma has a considerably higher self-stabilization rate compared to the MCC-based probe[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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性状 Solid
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分子量 491.30
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分子式 C16H10F4NNaO9S
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Color White to off-white
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SMILES
O=C([C@H]1CO[C@H](OC1)CN2C(C=CC2=O)=O)OC3=C(C(F)=C(C(F)=C3F)S(=O)(O[Na])=O)F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (203.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0354 mL | 10.1771 mL | 20.3542 mL | 50.8854 mL |
| 5 mM | 0.4071 mL | 2.0354 mL | 4.0708 mL | 10.1771 mL | |
| 10 mM | 0.2035 mL | 1.0177 mL | 2.0354 mL | 5.0885 mL | |
| 15 mM | 0.1357 mL | 0.6785 mL | 1.3569 mL | 3.3924 mL | |
| 20 mM | 0.1018 mL | 0.5089 mL | 1.0177 mL | 2.5443 mL | |
| 25 mM | 0.0814 mL | 0.4071 mL | 0.8142 mL | 2.0354 mL | |
| 30 mM | 0.0678 mL | 0.3392 mL | 0.6785 mL | 1.6962 mL | |
| 40 mM | 0.0509 mL | 0.2544 mL | 0.5089 mL | 1.2721 mL | |
| 50 mM | 0.0407 mL | 0.2035 mL | 0.4071 mL | 1.0177 mL | |
| 60 mM | 0.0339 mL | 0.1696 mL | 0.3392 mL | 0.8481 mL | |
| 80 mM | 0.0254 mL | 0.1272 mL | 0.2544 mL | 0.6361 mL | |
| 100 mM | 0.0204 mL | 0.1018 mL | 0.2035 mL | 0.5089 mL |
MDTF 関連分類
HY-150043A 関連分類
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