Meglutol-d3
Based on 1 Customer Validation
Meglutol-d3 is the deuterium labeled Meglutol. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.04%
- CAS 番号: 59060-36-5
- 分子式: C6H7D3O5
- 分子量:165.16
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 59060-36-5
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非標識Cas 503-49-1
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性状 Solid
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分子量 165.16
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分子式 C6H7D3O5
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Color White to off-white
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SMILES
OC(CC(C([2H])([2H])[2H])(O)CC(O)=O)=O
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別名
Dicrotalic acid-d3; 3-Hydroxy-3-methylglutaric acid-d3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
Methanol : 100 mg/mL (605.47 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol | 1 mM | 6.0547 mL | 30.2737 mL | 60.5473 mL | 151.3684 mL |
| 5 mM | 1.2109 mL | 6.0547 mL | 12.1095 mL | 30.2737 mL | |
| 10 mM | 0.6055 mL | 3.0274 mL | 6.0547 mL | 15.1368 mL | |
| 15 mM | 0.4036 mL | 2.0182 mL | 4.0365 mL | 10.0912 mL | |
| 20 mM | 0.3027 mL | 1.5137 mL | 3.0274 mL | 7.5684 mL | |
| 25 mM | 0.2422 mL | 1.2109 mL | 2.4219 mL | 6.0547 mL | |
| 30 mM | 0.2018 mL | 1.0091 mL | 2.0182 mL | 5.0456 mL | |
| 40 mM | 0.1514 mL | 0.7568 mL | 1.5137 mL | 3.7842 mL | |
| 50 mM | 0.1211 mL | 0.6055 mL | 1.2109 mL | 3.0274 mL | |
| 60 mM | 0.1009 mL | 0.5046 mL | 1.0091 mL | 2.5228 mL | |
| 80 mM | 0.0757 mL | 0.3784 mL | 0.7568 mL | 1.8921 mL | |
| 100 mM | 0.0605 mL | 0.3027 mL | 0.6055 mL | 1.5137 mL |