ML114
ML114 is a specific inhibitor of RBBP9 serine hydrolase, with an IC50 of 0.63 μM against recombinant RBBP9. ML114 can inhibit the proliferation of human pluripotent stem cells (hPSCs) by regulating the expression of NFYA and other factors, but does not induce differentiation. ML114 can be used in the research of diseases such as retinoblastoma.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 866149-26-0
- 分子式: C12H16N2O2S
- 分子量:252.33
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Phospholipase アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
0.64 μM
Compound: 18
|
Displacement of fluorophosphate-rhodamine from RBBP9 transfected in human HEK293T cells proteomes after 30 mins by SDS-PAGE gel fluorescence assay
Displacement of fluorophosphate-rhodamine from RBBP9 transfected in human HEK293T cells proteomes after 30 mins by SDS-PAGE gel fluorescence assay
|
[PMID: 20207142] |
化学情報
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CAS 番号 866149-26-0
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分子量 252.33
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分子式 C12H16N2O2S
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SMILES
C/C(C1=NC=CS1)=N\OC(C2CCCCC2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)