MV152
MV152 serves as the inactive control for the proteasome activity probe MV151. It contains a reduced ethyl sulfone group that replaces the vinyl sulfone reactive group of MV151, while retaining the identical fluorescent reporter group and peptide recognition sequence. MV152 does not bind to the active site of the proteasomal catalytic subunit β, does not induce peptide-mediated elevation of 20S proteasome activity, and does not label the proteasomal catalytic subunit β in brain tissue homogenates. MV152 can be used as an inactive negative control in proteasome-related experiments.
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- CAS 番号: 945611-89-2
- 分子式: C59H93BF2N8O9S
- 分子量:1139.29
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
MV152 does not label the active β subunits of purified human 20S proteasome[1].
MV152 does not label the active β subunits of the proteasome in brain tissue homogenates[1].
MV152 (10 min) does not alter the chymotrypsin-like activity of purified 20S proteasome under the experimental conditions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 945611-89-2
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分子量 1139.29
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分子式 C59H93BF2N8O9S
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SMILES
O=C(CCC1=C(C)[N-]2[B+3]([F-])([F-])[N]3=C(C4=CC=C(OC)C=C4)C=CC3=CC2=C1C)NCCCCCC(NCCCCCC(NCCCCCC(NC(CC(C)C)C(NC(CC(C)C)C(NC(CC(C)C)CCS(=O)(C)=O)=O)=O)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MV152 関連分類
HY-183468 関連分類
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