Oleoylestrone
Oleoylestrone, an adipose tissue-derived hormonal signal, is a slimming agent that decreases food intake and maintains energy expenditure.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 180003-17-2
- 分子式: C36H54O3
- 分子量:534.81
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | EC50 |
~ 10 nM
Compound: 1-oleoyl (table 1)
|
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells
|
[PMID: 15857137] |
Oleoylestrone is an adipose tissue-derived hormonal signal that elicits the decrease of body fat stores. This is accomplished by decreasing white adipose tissue mass through apoptosis and massive loss of lipid, accompanied by a decrease in food intake and the maintenance of energy expenditure[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 180003-17-2
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分子量 534.81
-
分子式 C36H54O3
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SMILES
C[C@]12[C@]([H])([C@@]3(CCC4=C([C@]3(CC2)[H])C=CC(OC(CCCCCCC/C=C\CCCCCCCC)=O)=C4)[H])CCC1=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)