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製品番号: HY-184755

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Poly(methacrylic acid)

(別名: PMAA)

Poly(methacrylic acid) (PMAA) is a pH/ionic strength-responsive swelling agent and polycation complexing agent. Poly(methacrylic acid) undergoes reversible swelling and size changes through carboxylic acid ionization and sodium ion charge shielding. As a weak polyacid, Poly(methacrylic acid) forms cross-linked hydrogels and hollow capsules for the entrapment and storage of macromolecules. Poly(methacrylic acid) forms electrostatic complexes with polycations to reduce capsule permeability, and high-salt conditions disrupt such complexes to enable macromolecule release.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 25087-26-7
分子式: (C₄H₆O₂)_n

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Poly(methacrylic acid) 構造式

CAS 番号: 25087-26-7

容量

価格（税別）

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Poly(methacrylic acid) can serve as a biocompatible hydrogel matrix to achieve non-Fickian, pH-dependent in vitro controlled release of Metoclopramide hydrochloride (HY-17382)^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 25087-26-7
分子式 (C₄H₆O₂)_n
SMILES

CCC(C)(C(O)=O)C.[n]
別名

PMAA
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Kozlovskaya V, Kharlampieva E, Mansfield M L, et al. Poly (methacrylic acid) hydrogel films and capsules: response to pH and ionic strength, and encapsulation of macromolecules[J]. Chemistry of materials, 2006, 18(2): 328-336.

[2]. Gunther EC, et al. Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists. Cell Rep. 2019 Jan 2;26(1):145-158.e8. [Content Brief]

[3]. Garcıa D M, et al. Synthesis and characterization of poly (methacrylic acid) hydrogels for metoclopramide delivery[J]. European Polymer Journal, 2004, 40(8): 1637-1643.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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