QM295
Based on 1 Customer Validation
QM295 is an endoplasmic reticulum oxidation 1 (ERO1) inhibitor with selectively reversible thiol reactivity. QM295 can be used for the research of endoplasmic reticulum stress.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.53%
- CAS 番号: 1241046-32-1
- 分子式: C17H13NO4
- 分子量:295.29
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
QM295 (25 μM, 50 μM) inhibits the development of AUR fluorescence in a kinetic assay with an IC50 value of 1.9 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1241046-32-1
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性状 Solid
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分子量 295.29
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分子式 C17H13NO4
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Color Light yellow to yellow
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SMILES
O=C1C(/C=C2C=CC(C(OC)=C/2)=O)=C(C3=CC=CC=C3)NO1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 100 mg/mL (338.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3865 mL | 16.9325 mL | 33.8650 mL | 84.6625 mL |
| 5 mM | 0.6773 mL | 3.3865 mL | 6.7730 mL | 16.9325 mL | |
| 10 mM | 0.3387 mL | 1.6933 mL | 3.3865 mL | 8.4663 mL | |
| 15 mM | 0.2258 mL | 1.1288 mL | 2.2577 mL | 5.6442 mL | |
| 20 mM | 0.1693 mL | 0.8466 mL | 1.6933 mL | 4.2331 mL | |
| 25 mM | 0.1355 mL | 0.6773 mL | 1.3546 mL | 3.3865 mL | |
| 30 mM | 0.1129 mL | 0.5644 mL | 1.1288 mL | 2.8221 mL | |
| 40 mM | 0.0847 mL | 0.4233 mL | 0.8466 mL | 2.1166 mL | |
| 50 mM | 0.0677 mL | 0.3387 mL | 0.6773 mL | 1.6933 mL | |
| 60 mM | 0.0564 mL | 0.2822 mL | 0.5644 mL | 1.4110 mL | |
| 80 mM | 0.0423 mL | 0.2117 mL | 0.4233 mL | 1.0583 mL | |
| 100 mM | 0.0339 mL | 0.1693 mL | 0.3387 mL | 0.8466 mL |