SARS-CoV-IN-3
Based on 1 publication(s) in Google Scholar
SARS-CoV-IN-3 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-3 shows anti-Coronavirus activity with an EC50 of 3.6 μM in Vero cells. SARS-CoV-IN-3 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 11.7 and 20.4 nM; and IC90s of 29.19 and 56 nM; respectively. SARS-CoV-IN-3 reduces HIV-1-induced cytopathic effect with an EC50 of 10 μM in MT-4 cells.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.36%
- CAS 番号: 888958-27-8
- 分子式: C25H20ClFeN3O
- 分子量:469.74
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 SARS-CoV-IN-3
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生物活性
製品説明
IC50 & Target
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Plasmodium |
HIV-1 |
体外実験
SARS-CoV-IN-3 (Compound 4) inhibits in vitro growth of Plasmodium falciparum far better than Chloroquine (CQ) [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 888958-27-8
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性状 Solid
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分子量 469.74
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分子式 C25H20ClFeN3O
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Color Light yellow to yellow
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SMILES
CCN(CCO)CC12=C3[Fe+2]145678(C9=C43)([C-]%10C5=C6C7=C8%10)[C-]29CNC%11=CC=NC%12=C%11C=CC(Cl)=C%12
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Nucleic Acids Res
COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics. [Abstract]2021 Jan 8;49(D1):D1113-D1121. PMID: 33166390
溶剤 & 溶解度
体外:
DMSO : 7.81 mg/mL (16.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (284 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1288 mL | 10.6442 mL | 21.2884 mL | 53.2209 mL |
| 5 mM | 0.4258 mL | 2.1288 mL | 4.2577 mL | 10.6442 mL | |
| 10 mM | 0.2129 mL | 1.0644 mL | 2.1288 mL | 5.3221 mL | |
| 15 mM | 0.1419 mL | 0.7096 mL | 1.4192 mL | 3.5481 mL |
SARS-CoV-IN-3 関連分類
HY-135858 関連分類
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