115 Results for "

parathyroid

" in MedChemExpress (MCE) Product Catalog:
Products (115)

115 Results for "parathyroid" in MCE Product Catalog:

  • Targets Recommended:
16
16 Publications Verification
製品番号: HY-50919
CAS 番号: 131918-61-1
Target:  

VD/VDR

研究分野:  

Metabolic Disease Cancer

Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.
loading...
    loading...
11
11 Cited Publications
製品番号: HY-P0059
CAS 番号: 52232-67-4
別名: Human parathyroid hormone-(1-34); hPTH (1-34)
研究分野:  

Others Cancer

Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research .
loading...
    loading...
4
4 Cited Publications
製品番号: HY-N2098
CAS 番号: 477-85-0
Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein .
loading...
    loading...
3
3 Cited Publications
製品番号: HY-17613
CAS 番号: 870964-67-3
別名: KHK7580
Target:  

CaSR

研究分野:  

Metabolic Disease

Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
loading...
    loading...
3
3 Cited Publications
製品番号: HY-108742
CAS 番号: 247062-33-5
純度:  99.91%
別名: BA 058; BIM 44058
Target:  

PTHR Arrestin

研究分野:  

Metabolic Disease Cancer

Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis .
loading...
    loading...
3
3 Cited Publications
製品番号: HY-P1252
CAS 番号: 12583-68-5
研究分野:  

Metabolic Disease

Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis .
loading...
    loading...
3
3 Cited Publications
製品番号: HY-108742A
純度:  99.86%
別名: BA 058 TFA; BIM 44058 TFA
Target:  

Arrestin PTHR

Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .
loading...
    loading...
2
2 Cited Publications
製品番号: HY-P1955A
CAS 番号: 1334237-71-6
別名: Velcalcetide hydrochloride; AMG 416 hydrochloride; KAI-4169 hydrochloride
Target:  

CaSR

研究分野:  

Endocrinology

Etelcalcetide hydrochloride (AMG 416 hydrochloride; KAI-4169 hydrochloride) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease .
loading...
    loading...
2
2 Cited Publications
製品番号: HY-P2279
CAS 番号: 98614-76-7
Parathyroid hormone (1-34) (rat) is a parathyroid hormone. Parathyroid hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis .
loading...
    loading...
2
2 Cited Publications
製品番号: HY-P2279A
Parathyroid hormone (1-34) (rat) (acetate) is a parathyroid hormone. Parathyroid hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis .
loading...
    loading...
2
2 Cited Publications
製品番号: HY-N0546
CAS 番号: 260413-62-5
別名: Nuezhenoside
Ligustroflavone is an orally active flavonoid compound. Ligustroflavone can be extracted from Ligustrum lucidum. Ligustroflavone antagonizes the calcium-sensing receptor (CaSR), inhibits the RIPK1/RIPK3/MLKL pathway, and downregulates TGF-β/Smad signaling. Ligustroflavone regulates calcium metabolism, protects bone tissue, reduces cerebral ischemic injury, and inhibits liver fibrosis. Ligustroflavone can be used in the study of diabetic osteoporosis, ischemic stroke, and liver fibrosis .
loading...
    loading...
1
1 Cited Publications
製品番号: HY-112171
CAS 番号: 5875-41-2
純度:  ≥98.0%
別名: γ-Glu-Ala
γ-L-Glutamyl-L-alanine (γ-Glu-Ala), composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function .
loading...
    loading...
1
1 Cited Publications
製品番号: HY-P71060
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: parathyroid hormone; PTH; Parathormone; Parathyrin; PTH
Species:  
Source:  
loading...
    loading...
製品番号: HY-100856
CAS 番号: 1613373-33-3
純度:  99.67%
Target:  

PTHR

研究分野:  

Endocrinology

PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.
loading...
    loading...
製品番号: HY-14401
CAS 番号: 787583-71-5
純度:  99.88%
別名: CLTX-305; JTT-305; MK-5442
Encaleret (CLTX-305) is an orally active antagonist of the calcium-sensing receptor (CaSR), with an IC50 of 12 nM. Encaleret exerts its effect by inhibiting the excessive activity of functional gain-of-function CaSR variants, and can restore blood calcium levels, promote the secretion of parathyroid hormone, improve magnesium and phosphorus metabolism, and increase urinary calcium excretion. Encaleret can be used in the research of diseases such as osteoporosis and autosomal dominant hypocalcemia type 1 .
loading...
    loading...
製品番号: HY-A0245
CAS 番号: 67-96-9
Target:  

VD/VDR

研究分野:  

Metabolic Disease

Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) .
loading...
    loading...
製品番号: HY-15103
CAS 番号: 862907-48-0
純度:  99.96%
Target:  

PTHR Androgen Receptor

研究分野:  

Cancer

AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC50 value of 0.82 μM. AH3960 also serves as an agonist of parathyroid hormone receptor-1 (PTHR1) .
loading...
    loading...
製品番号: HY-P2426
CAS 番号: 118102-98-0
研究分野:  

Metabolic Disease

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation .
loading...
    loading...
製品番号: HY-P10909
CAS 番号: 2925554-87-4
別名: MBX 2109
研究分野:  

Endocrinology

Canvuparatide (MBX 2109) is a prodrug for parathyroid hormone (PTH) peptide that releases the bioactive PTH[1-32] peptide agonist that retains a fatty acylated lysine (Lys33) at the C-terminus, thereby extending the halflife of Canvuparatide. Canvuparatide can be used for the symptoms of hypoparathyroidism such as hypocalcemia and hyperphosphatemia .
loading...
    loading...
製品番号: HY-148350
CAS 番号: 3032750-17-4
純度:  99.47%
Target:  

PTHR

研究分野:  

Cancer

DS69910557 is a potent, selective and orally activehuman parathyroid hormone receptor 1 (hPTHR1) antagonist. DS69910557 has antagonistic activity for PTHR1 with an IC50 value of 0.08 μM. DS69910557 can be used for the research of hyperparathyroidism, hypercalcemia of malignancy and osteoporosis .
loading...
    loading...