SSR180711
Based on 1 Customer Validation
SSR180711 is a potent and subtype-selective α7 agonist with activity in Alzheimer's disease and schizophrenia research. SSR180711 can be used to study subtypes of intracerebral hemorrhage associated with cerebral small vessel disease. SSR180711 shows potential in electrophysiological and behavioral studies to evaluate its effects on cognitive function. SSR180711 also has potential for studying cerebrovascular lesions and their effects.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.52%
- CAS 番号: 298198-52-4
- 分子式: C14H17BrN2O2
- 分子量:325.20
-
保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
More
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| GH4-C1 | EC50 |
0.9 μM
Compound: 29, SSR180711
|
Partial agonist activity at human alpha7 nAChR expressed in GH4C1 cells relative to acetylcholine
Partial agonist activity at human alpha7 nAChR expressed in GH4C1 cells relative to acetylcholine
|
[PMID: 21919481] |
| HEK293 | IC50 |
>3160 nM
Compound: 5
|
Displacement of [3H]LY278584 from human 5HT3 receptor expressed in HEK293 cells
Displacement of [3H]LY278584 from human 5HT3 receptor expressed in HEK293 cells
|
[PMID: 19576766] |
| IMR-32 | IC50 |
>6480 nM
Compound: 5
|
Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cells
Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cells
|
[PMID: 19576766] |
| Oocyte | EC50 |
4.4 μM
Compound: 29, SSR180711
|
Partial agonist activity at human alpha7 nAChR expressed in Xenopus oocytes relative to acetylcholine
Partial agonist activity at human alpha7 nAChR expressed in Xenopus oocytes relative to acetylcholine
|
[PMID: 21919481] |
化学情報
-
CAS 番号 298198-52-4
-
性状 Solid
-
分子量 325.20
-
分子式 C14H17BrN2O2
-
Color Off-white to light brown
-
SMILES
O=C(N1CCN2CCC1CC2)OC3=CC=C(C=C3)Br
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
-
データシート (271 KB)
-
SDS (644 KB)
- English - EN (644 KB)
- Français - FR (644 KB)
- Deutsch - DE (644 KB)
- Norwegian - NO (644 KB)
- Español - ES (644 KB)
- Swedish - SV (644 KB)
- Italian - IT (644 KB)
- Korean - KR (644 KB)
- Portuguese - PT (644 KB)
-
取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
SSR180711 関連分類
HY-167824 関連分類
Powered by Bioz