T-1840383
T-1840383 is a potent, ATP-competitive inhibitor of c-Met/VEGFR-2, with the IC50s of 1.9 nM, 7.7 nM, 2.2 nM and 5.5 nM for c-Met, VEGFR1, VEGFR2 and VEGFR3, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1195779-24-8
- 分子式: C30H25ClFN5O4
- 分子量:574.00
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
VEGFR アイソフォーム固有の製品をすべて表示
More
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | IC50 |
1.8 nM
Compound: 26
|
Cytotoxicity against VEGF-stimulated HUVEC assessed as growth inhibition after 120 hrs by CCK-8 assay
Cytotoxicity against VEGF-stimulated HUVEC assessed as growth inhibition after 120 hrs by CCK-8 assay
|
[PMID: 24216091] |
| MKN-45 | IC50 |
5 nM
Compound: 26
|
Cytotoxicity against human MKN45 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
Cytotoxicity against human MKN45 cells assessed as growth inhibition after 72 hrs by CCK-8 assay
|
[PMID: 24216091] |
化学情報
-
CAS 番号 1195779-24-8
-
分子量 574.00
-
分子式 C30H25ClFN5O4
-
SMILES
O=C(NC1=CC=C(C(F)=C1)OC2=CN3C(C=C2)=NC(NC(C4CC4)=O)=C3)C5=CC=C(N(C5=O)C6=CC=CC=C6)C.Cl
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
T-1840383 関連分類
HY-120661 関連分類
Powered by Bioz