Testosterone/BSA
Based on 1 publication(s) in Google Scholar
Testosterone/BSA, a conjugate of Testosterone (HY-113415) and bovine serum albumin (BSA), acts as a nuclear transporter and cytoplasmic accumulator. Testosterone/BSA can enter the nuclei of rat testicular spermatocytes, spermatids and rat liver endothelial cells, while the antigenicity of BSA remains intact. Testosterone/BSA accumulates in the cytoplasm of rat hepatocytes in granular form. Testosterone/BSA can be used to investigate the membrane-initiated or non-genomic activities of steroid hormones.
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
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MedChemExpress（MCE）の使用を引用している文献 Testosterone/BSA
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生物活性
製品説明
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wistar rats (male, 10 weeks old)[1]
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Dosage:1 mg
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Administration:i.v.; single dose
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Result:Detected FITC fluorescence (indicating intact BSA antigenicity) in the nuclei of spermatocytes and spermatids in some rat testicular seminiferous tubules.
Detected FITC fluorescence in the nuclei of rat liver sinusoidal endothelial cells.
Observed no fluorescence in the nuclei of rat liver hepatocytes, hepatic stellate cells, or Kupffer cells, though granular fluorescence was seen in the cytoplasm of some hepatocytes.
化学情報
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性状 Liquid
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Color Colorless to light yellow
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SMILES
[Testosterone/BSA]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Asian J Androl
Inhibition of 5αR2 promotes postoperative wound repair in BPH patients after TURP by alleviating fibrosis and inflammation. [Abstract]2025 Oct 28. PMID: 41147439
プロトコル
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Endothelial Tube Formation Assay
Endothelial tube formation assay evaluates the ability of endothelial cells to attach, migrate, align, and organize into capillary-like networks when cultured on gelled basement membrane extract or Matrigel; the readout is the morphology and quantity of tube-like networks, which reflects an in vitro endothelial morphogenesis step related to angiogenesis. Basement membrane extract/Matrigel provides laminin-rich extracellular matrix cues that support endothelial differentiation into capillary-like structures, but it can contain biologically active growth factors, so growth-factor-reduced matrix is preferred when testing defined angiogenic stimulators or inhibitors.
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
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- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Testosterone/BSA 関連分類
HY-NP181 関連分類
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