TM11
Based on 1 Customer Validation
TM11, a Tanshinone mimic, is a potent HuR inhibitor that can inhibit HuR-RNA complex formation. TM11 reduces LPS-induced inflammatory response in murine macrophages.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- Assay : 97.49%
- 分子式: C18H11NO5S
- 分子量:353.35
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保管条件:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
生物活性
製品説明
化学情報
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性状 Solid
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分子量 353.35
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分子式 C18H11NO5S
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Color Dark purple to black
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SMILES
O=C1C2=C(N(S(=O)(C3=CC=CC=C3)=O)C=C2C4=CC=CO4)C=CC1=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (141.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8301 mL | 14.1503 mL | 28.3006 mL | 70.7514 mL |
| 5 mM | 0.5660 mL | 2.8301 mL | 5.6601 mL | 14.1503 mL | |
| 10 mM | 0.2830 mL | 1.4150 mL | 2.8301 mL | 7.0751 mL | |
| 15 mM | 0.1887 mL | 0.9434 mL | 1.8867 mL | 4.7168 mL | |
| 20 mM | 0.1415 mL | 0.7075 mL | 1.4150 mL | 3.5376 mL | |
| 25 mM | 0.1132 mL | 0.5660 mL | 1.1320 mL | 2.8301 mL | |
| 30 mM | 0.0943 mL | 0.4717 mL | 0.9434 mL | 2.3584 mL | |
| 40 mM | 0.0708 mL | 0.3538 mL | 0.7075 mL | 1.7688 mL | |
| 50 mM | 0.0566 mL | 0.2830 mL | 0.5660 mL | 1.4150 mL | |
| 60 mM | 0.0472 mL | 0.2358 mL | 0.4717 mL | 1.1792 mL | |
| 80 mM | 0.0354 mL | 0.1769 mL | 0.3538 mL | 0.8844 mL | |
| 100 mM | 0.0283 mL | 0.1415 mL | 0.2830 mL | 0.7075 mL |