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United States

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製品番号: HY-N12603

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Typhatifolin B

Typhatifolin B (Compd 2), an anti-cancer agent, could remarkably induce cell apoptosis and G0/G1 cycle arrest, as well as block cell migration and invasion.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₃₄H₃₂O₅
分子量:520.61

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Typhatifolin B 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Typhatifolin B (Compd 2), an anti-cancer agent, could remarkably induce cell apoptosis and G0/G1 cycle arrest, as well as block cell migration and invasion^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
4T1	IC₅₀	2.82 μM Compound: 2; TTB	Cytotoxicity against mouse 4T1 cells assessed as cell viability by MTT assay Cytotoxicity against mouse 4T1 cells assessed as cell viability by MTT assay	[PMID: 38387332]
A549	IC₅₀	3.21 μM Compound: 2; TTB	Cytotoxicity against human A549 cells assessed as cell viability by MTT assay Cytotoxicity against human A549 cells assessed as cell viability by MTT assay	[PMID: 38387332]
BEAS-2B	IC₅₀	5.27 μM Compound: 2; TTB	Cytotoxicity against human BEAS-2B cells assessed as cell viability by MTT assay Cytotoxicity against human BEAS-2B cells assessed as cell viability by MTT assay	[PMID: 38387332]
HeLa	IC₅₀	2.2 μM Compound: 2; TTB	Cytotoxicity against human HeLa cells assessed as cell viability by MTT assay Cytotoxicity against human HeLa cells assessed as cell viability by MTT assay	[PMID: 38387332]
HFF	IC₅₀	5.91 μM Compound: 2; TTB	Cytotoxicity against human HFF cells assessed as cell viability by MTT assay Cytotoxicity against human HFF cells assessed as cell viability by MTT assay	[PMID: 38387332]
MCF7	IC₅₀	8.64 μM Compound: 2; TTB	Cytotoxicity against human MCF7 cells assessed as cell viability by MTT assay Cytotoxicity against human MCF7 cells assessed as cell viability by MTT assay	[PMID: 38387332]
MDA-MB-231	IC₅₀	4.33 μM Compound: 2; TTB	Cytotoxicity against human MDA-MB-231 cells assessed as cell viability by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell viability by MTT assay	[PMID: 38387332]

体外実験

Typhatifolin B (Compd 2) exhibits IC₅₀ values of 4.33 μM, 8.64 μM, 2.82 μM, 2.20 μM, 3.21 μM, 5.27 μM in MDA-MB231, MCF-7, 4T1, Hela, A549, BEAS-2B, HFF cells, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

分子量 520.61
分子式 C₃₄H₃₂O₅
SMILES

O=C1C[C@@](OC2=C1C(O)=C([C@@](/C=C/C[C@@H](O)CCC3=CC=CC=C3)([H])C4=CC=CC=C4)C(O)=C2)([H])C5=CC=CC=C5
Structure Classification
- Flavonoids
- Flavonones
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (272 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Yu-Peng Li, et al. Rare flavanone-diarylheptanoid hybrids from Typha angustifolia shows anti breast cancer activity via activating TGF-β1/Smad signaling pathway. European Journal of Medicinal Chemistry. Volume 268, 15 March 2024, 116220.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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