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製品番号: HY-155053

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ZIKV-IN-6

ZIKV-IN-6 (compound 22) is an inhibitor of Zika virus (ZIKV), with low cytotoxicity (CC₅₀＞50 μM). ZIKV-IN-6 binds to ZIKV RdRp directly and inhibits viral RNA synthesis by ZIKV NS5. ZIKV-IN-6 suppresses the excessive inflammatory response and pyroptosis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₂₇H₂₉NO₆
分子量:463.52

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

ZIKV-IN-6 構造式

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

IC₅₀ & Target

Zika virus (ZIKV)^[1]

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	CC₅₀	>50 μM Compound: 22	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 37421888]
JEG-3	CC₅₀	54.7 μM Compound: 22	Cytotoxicity against human JEG-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human JEG-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 37421888]
SNB-19	CC₅₀	66.1 μM Compound: 22	Cytotoxicity against human SNB-19 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SNB-19 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 37421888]
Vero	CC₅₀	65.4 μM Compound: 22	Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 37421888]

化学情報

分子量 463.52
分子式 C₂₇H₂₉NO₆
SMILES

O=C1C2=C(C(O)=C(N3CCC(C4=CC=CC=C4)CC3)C=C2O)C(C5=C1C[C@@](C)(O)[C@@](C)(O)C5)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Zhu Y, et al. Design, synthesis, and biological evaluation of a series of new anthraquinone derivatives as anti-ZIKV agents. Eur J Med Chem. 2023 Oct 5;258:115620. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

お問い合わせ

Amount: USD 0.00

生物活性
- 製品説明
- IC₅₀ & Target
化学情報
純度とドキュメンテーション
参考文献

製品名:
製品番号:
数量:
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ZIKV-IN-6

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示

生物活性

製品説明

IC50 & Target

Cellular Effect

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

ZIKV-IN-6 関連分類

HY-155053 関連分類

Bioz

Keywords

最近チェックした製品

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