ZW290
Based on 1 Customer Validation
ZW290 is a compound to activate brown adipose tissue (BAT) thermogenic function. ZW290 increases the expression of uncoupling Protein 1 (UCP1) protein and inhibits ATP synthesis in BAT.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.60%
- CAS 番号: 2411852-67-8
- 分子式: C20H18N2O6S
- 分子量:414.43
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
ZW290 in brown adipose tissue (BAT) induces nonshivering thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids and increasing UCP1 protein levels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Male Kunming (KM) mice (20 g) keeping under acute cold exposure (-20°C)[1]
-
Dosage:25 mg/kg, 50 mg/kg, or 100 mg/kg
-
Administration:Oral gavage; once a day; for 7 days
-
Result:Notably decreased the size of lipid droplets in BAT and increased the content of mitochondria and the expression of UCP1 in BAT and WAT.
化学情報
-
CAS 番号 2411852-67-8
-
性状 Solid
-
分子量 414.43
-
分子式 C20H18N2O6S
-
Color Yellow to brown
-
SMILES
O=C1N(C2=CC=C(C=C2)OC)C(N/C1=C\C3=CC(OC)=C(C=C3)OCC(O)=O)=S
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
-
データシート (269 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)