JQ-1-Azidopropylamine
Based on 1 Customer Validation
JQ-1-Azidopropylamine is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for BRD4 (HY-78695) and a PROTAC linker (HY-151862), which recruits E3 ligases. JQ-1-Azidopropylamine can be used for synthesis of PROTAC JY-21 (HY-174975).
For research use only. We do not sell to patients.
- Purity: 99.5700%
- CAS No.: 2915642-70-3
- Formula: C22H23ClN8OS
- Molecular Weight:482.99
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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BRD4 |
Chemical Information
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CAS No. 2915642-70-3
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Appearance Solid
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Molecular Weight 482.99
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Formula C22H23ClN8OS
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Color White to off-white
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SMILES
CC1=NN=C2[C@@H](N=C(C3=C(N12)SC(C)=C3C)C4=CC=C(C=C4)Cl)CC(NCCCN=[N+]=[N-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (207.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0704 mL | 10.3522 mL | 20.7044 mL | 51.7609 mL |
| 5 mM | 0.4141 mL | 2.0704 mL | 4.1409 mL | 10.3522 mL | |
| 10 mM | 0.2070 mL | 1.0352 mL | 2.0704 mL | 5.1761 mL | |
| 15 mM | 0.1380 mL | 0.6901 mL | 1.3803 mL | 3.4507 mL | |
| 20 mM | 0.1035 mL | 0.5176 mL | 1.0352 mL | 2.5880 mL | |
| 25 mM | 0.0828 mL | 0.4141 mL | 0.8282 mL | 2.0704 mL | |
| 30 mM | 0.0690 mL | 0.3451 mL | 0.6901 mL | 1.7254 mL | |
| 40 mM | 0.0518 mL | 0.2588 mL | 0.5176 mL | 1.2940 mL | |
| 50 mM | 0.0414 mL | 0.2070 mL | 0.4141 mL | 1.0352 mL | |
| 60 mM | 0.0345 mL | 0.1725 mL | 0.3451 mL | 0.8627 mL | |
| 80 mM | 0.0259 mL | 0.1294 mL | 0.2588 mL | 0.6470 mL | |
| 100 mM | 0.0207 mL | 0.1035 mL | 0.2070 mL | 0.5176 mL |