JY-21
JY-21 is a BRD4 PROTAC degrader with a DC50 of 3.797 μM. JY-21 has a potent anticancer activity against MDA-MB-231 cells. Pink: BRD4 ligand (HY-78695); Blue: E3 ligase ligand (HY-174994); Black: linker (HY-151862)
(Pink: BRD4 ligand (HY-78695); Blue: Ligands for E3 Ligase ligand (HY-174994); Black: linker (HY-151862)).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C42H50ClN11O4SSi
- Peso molecular:868.52
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas PROTACs
More
Actividad biológica
|
BRD4 3.797 μM (DC50) |
Chemical Information
-
Peso molecular 868.52
-
Fòrmula C42H50ClN11O4SSi
-
SMILES
CC1=C(C(C(C2=CC=C(C=C2)Cl)=N[C@H]3CC(NCCCN4C=C(N=N4)COC5=CC=C(C([N+]([O-])=O)=C5)/N=N/C#C[Si](C(C)C)(C(C)C)C(C)C)=O)=C(N6C3=NN=C6C)S1)C
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)